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糖尿病视网膜病变中大视杯发生率探讨
引用本文:李德姣,王宁利,陈术,李爱红.糖尿病视网膜病变中大视杯发生率探讨[J].中国实用眼科杂志,2008,26(4).
作者姓名:李德姣  王宁利  陈术  李爱红
作者单位:北京中日友好医院,北京同仁医院眼科中心,北京,100029
摘    要:目的 研究糖尿病视网膜病变中大视杯的发生率,对结果进行分析,探讨其发生机制.方法 选择糖尿病视网膜病变患者104例208只眼,进行视盘眼底彩照,图像分析仪测定其C/D比值,根据分析结果进行分组,C/D≤0.3组和C/D≥0.6组.比较两组间的眼压和视网膜循环时间之间的差异.结果 糖尿病视网膜病变中C/D≤0.3的占51.92%;C/D≥0.6的占14.90%.C/D≤0.3组和C/D≥0.6组的眼压分别为(14.91±2.15)mmHg;(13.70±2.73)mmHg(P>0.05)差异无统计学意义;C/D≥0.6组的视网膜循环时间为(2.69±1.58)S,较C/D≤0.3组(1.90+0.58)S明显延迟(P<0.05),差异有统计学意义.结论 糖尿病视网膜病变中C/D比值大于0.6的比率显著高于一般人群.造成C/D比值增加的因素考虑以视网膜缺血为主,而非眼压增高所致,说明视网膜血液循环障碍对C/D比值的扩大有一定影响.

关 键 词:糖尿病视网膜病变  C/D比值  视网膜循环时间眼压

To study the incidence of large optic cup in Diabetic retinopathy and the correlation factors
Abstract:Objective To study the incidence of large optic cup in Diabetic retinopathy and analysis the correlation associated factors and the mechanism.Methods the study included the 208 eyes of 104 diabetics,to evaluate their color fundus pictures with image analysis computer,according to the ratio of cup/disc(C/D),divided the cases into two groups:CD ratio less than 0.3 and CD ratio more than 0.6;To compare their intraocular pressure and retinal circulation time(RCT).Results the incidence of C/D 40.3 in diabetics Was 51.92%;C/D≥0.6 was 14.90%:the intraocular pressure of the two groups were(14.91±2.15)mmHg;(13.70±2.73、mmHg,P>0.05,had no statistic difference;the RCT of C/D≥0.6 group was 2.69±1.58second delayed thanC/D≤0.3 group 1.90+0.58second,P<0.05,had statistic difference.Conclusions the ratio of C/D≥0.6 in diabetic retinopathy was higher thanth at in common people.the reason mostly associated with retinal ischemic ,the intraoculer pressure contributing less in this function.Indicated the disfunction of retinal circulation in diabetics affected the big C/D ratio.
Keywords:Diabetic retinopathy C/D ratio  Retinal circulation time(RCT)  Intraocular pressure
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