开胸术后硬膜外镇痛对心功能的影响

低浓度（０．２５％）布比卡因间断硬膜外腔注入，用于开胸术后持续镇痛，观察时心功能的影响，与未用硬膜外阻滞组进行比较。结果：两组间术前、术后８ｈ各参数无显著差异（Ｐ〉０．０５），术后１６、２４ｈ相差显著（Ｐ〈０．０５）；未用硬膜外阻滞镇痛组术后８、１６、２４ｈ各参数与术前比相差显著（Ｐ〈０．０５），硬膜外阻滞镇痛与术前比，８ｈ相差显著（Ｐ〈０．０５），１６ｈ部分参数无显著差异（Ｐ〈０．０５），２４ｈ

THE INFLUENCE OF EPIDURAL BLOCK FOR POSTOPERATIVE ANALGESIA ON CARDIAC FUNCTION IN PATIENTS UNDERGOING THORACOTOMY

Fourty petients were included for the study of the influence of postoperative analgesia on the cardiac function in patients undersoing thoracotomy. 0. 25% bupivacaine was intermittently administered into epidural space in analgesia group (n=20) after operation. In control group (n=20), no epidural block but meperidine i. m. was used for postoperative analgesia. Results showed that no stutistical differences in cardiac function was found preoperatively and in the first 8 hours after operation between two groups (P>0.05). However obvious differences were found (P<0.05) in 16~ 24 hours postoperatively. The parameters of cardiac founction chAnged markedly (P<0.05) at 8, 16 and 24 hours postoperatively in control group, comparing to preoperative values. In analgesia group, all parameters changed significantly at 8 hours, some perameters returned to normal range at 16 hours, and all parameters but heart rate were normal at 24 hours petoperatively, comparing to the preoperative values. The results indicated that the cardiac founction did not resume to normal until 24 hours after thoracotomy in control group. The epidural administration of low concentation bupivacaine for postoperative analgesia could help the cardiac function resuming to normal as early as 16 hours postoperatively. Such analgesic method did not affect respiratory function.