Expression of adhesion molecules by endothelial cells of early human decidua |
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| Authors: | Carmen G Tortosa M Luisa Vargas Miguel Cámara Pilar Alemán M José Montes Concepción Ruiz Enrique G Olivares |
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| Institution: | (1) Sectión de Inmunología, Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Universidad de Granada, E-18012 Granada, Spain;(2) Departamento de Anatomía Patológica, Facultad de Medicina, Universidad de Granada, E-18012 Granada, Spain |
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| Abstract: | The expression of adhesion molecules by endothelial cells (EC) of early human decidua was studied with monoclonal antibodies and the immunoperoxidase technique. Although E-selectin, INCAM-110 and VCAM-1 were poorly detected on decidual EC, ICAM-1, P-selectin and DR antigens were highly expressed by these cells, some of which showed high endothelial venule-like morphology. Our results suggest that decidual EC are activated, and are probably involved in the active recruitment of leucocytes. |
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| Keywords: | Decidua Endothelial cells Adhesion molecules Leucocyte recruitment |
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