栾树种子的化学成分研究

目的：分离鉴定栾树(Koelreuteria paniculata Laxm.)种子的化学成分。 方法：分别用石油醚回流提取和95% EtOH浸提, 硅胶柱色谱分离, IR,MS,UV,¹HNMR,¹³CNMR等方法确定结构。 结果：分得8个化合物,分别为3/-O-十四烷酰基-1-腈基-2-甲基-1,2-丙烯(1), 3-O-二十碳-14,15-烯酰基-1-腈基-2-甲基-1,2-丙烯(2), 3-O-二十碳-14,15-烯酰基-4-O-十八烷酰基-1-腈基-2-氧代亚甲基-1,2-丙烯(3), 3-O-(6′-亚油酰基-葡萄糖)-β-谷甾醇(4), 1-O-β-D-葡萄糖-2-O-油酸-3-O-十六烷酸甘油酯（5), 1-O-十六烷酸甘油酯（6), 14,15-二十碳烯酸（7)，三油酸甘油酯（8)。 结论：1～3为新化合物, 4～8系首次从该植物中分得, 并归属其波谱信号。

CHEMICAL CONSTITUENTS FROM THE SEEDS OF KOELREUTERIA PANICULATA LAXM

AIM: Isolation and structural elucidation of the seeds of the Chinese medicinal plant Koelreuteria paniculata Laxm. METHODS: The seeds were extracted with petroleum ether by percolation and the crude extracts were purified by using silica gel chromatography. IR,UV,MS,¹H and ¹³CNMR spectra were employed for structural identification. RESULTS: Eight compounds named 3-O-tetradecanoyl-1-cyano-2-methyl-1, 2-propene(1), 3-O-14,15-eicosylenoyl-1-cyano-2-methyl-1,2-propene(2) and 3-O-14, 15-eicosylenoyl-4-O-stearoyl-1-cyano-2-oxymethyl-1,2-propene(3), 3-O-(6′-linoleicoyl-β-D- glycopyranoside)-β-sitosterol(4), 1-O-β-D-glycopyrano-2-O-oleo-3-O-hexadecanolenin(5), 1-O-hexadecanolenin(6), 14，15-eicosenic acid(7), triolein(8) were isolated. CONCLUSION: Three new compounds in term of 3-O-tetradecanoyl-1-cyano-2-methyl-1,2-propene(1), 3-O-14, 15-eicosylenoyl-1-cyano-2-methyl-1, 2-propene(2) and 3-O-14, 15-eicosylenoyl-4-O-stearoyl-1-cyano-2-oxymethyl-1,2-propene(3), together with four other compounds were isolated from the seeds, and compounds 4～7 were obtained from this plant for the first time.