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| 盐酸克林霉素凝胶治疗寻常性痤疮的临床研究 | |
| 引用本文： | 陈兴平,李慎秋,李家文,陈映玲,徐世正.盐酸克林霉素凝胶治疗寻常性痤疮的临床研究[J].医药导报,2002,21(6):346-347. |
| 作者姓名： | 陈兴平 李慎秋 李家文 陈映玲 徐世正 |
| 作者单位： | 1. 华中科技大学同济医学院附属同济医院皮肤性病科,武汉,430030 2. 华中科技大学同济医学院 3. 武汉大学人民医院皮肤科,430070 |
| 摘 要： | 目的:评价盐酸克林霉素凝胶在治疗寻常性痤疮中的疗效和安全性.方法:寻常性痤疮患者200例,采用严格的多中心、双盲、随机平行对照试验的方法.治疗组100例应用1%盐酸克林霉素凝胶治疗,对照组100例应用1%克林霉素磷酸酯凝胶治疗,比较两组疗效.结果:治疗组有效率为84.0%,对照组为78.0%,经Ridit检验,两组疗效差异不显著;两组的不良反应均较轻.结论:1%盐酸克林霉素凝胶治疗寻常性痤疮是安全、有效的. |
| 关 键 词： | 克林霉素 盐酸 痤疮 寻常性 |
| 文章编号： | 1004-0781(2002)06-0346-02 |
| 修稿时间： | 2001年12月18 |
Clinical Study Of Clindamycin Hydrochloride Gel in the Treatment of Acne Vulgaris |
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| CHEN Xing ping,LI Shen qiu,LI Jia wen,CEHN Yin ling,XU Shi zheng.Clinical Study Of Clindamycin Hydrochloride Gel in the Treatment of Acne Vulgaris[J].Herald of Medicine,2002,21(6):346-347. | |
| Authors: | CHEN Xing ping LI Shen qiu LI Jia wen CEHN Yin ling XU Shi zheng |
| Abstract: | Objective:To evaluate the efficacy and safety of 1% clindamycin hydrochloride gel in the treatment of acne vulgaris. Methods:The effects of 1% clindamycin hydrochloride gel on acne vulgaris were observed in comparison with 1% clindamycing phosphate gel in a multicentre, double blind, randomized, and parallel controlled trial. Results:The effective rate in experiment group was 84.0% and the effective rate in control group was 78.0%. No significant difference was found in efficacy between the two groups using ridit test. The side effects of both medicine were mild. Conclusion:1% clindamycin hydrochloride gel is safe and effective in the treatmeat of acne vulgaris. |
| Keywords: | Clindamycin hydrochloride gel Acne vulgaris |
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