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Assessment of blood stasis in left-atrial appendage with electron-beam CT: filling delay in atrial fibrillation |
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| Authors: | Tadashi Nakanishi Seiki Hamada Makoto Takamiya Sachio Kuribayashi Hiroaki Naito |
| Affiliation: | (1) Department of Radiology, National Cardiocascular Center, 5-7-1 Fujishirodai, Suita, 565 Osaka, Japan;(2) Biomedical Research Center, Osaka University School of Medicine, 2-2 Yamadaoka, Suite, 565 Osaka, Japan;(3) Present address: Department of Radiology, Hiroshima University School of Medicine, 1-2-3 Kasumi, Minami-ku, 734 Hiroshima, Japan |
| Abstract: | The left-atrial appendage (LAA) is the most frequent site of thrombus formation. The most probable reason is its anatomical structure and blood stasis. We hypothesized that peak time delay should occur in the LAA with stagnant blood flow. We measured peak time delay in LAA against left atrium with the flow-mode study of electron-beam CT for 49 patients (including 23 patients with atrial fibrillation [AF]). Volume-mode scannings were also performed to detect intracardiac thrombi. Patients with atrial fibrillation showed a larger value than those with sinus rhythm (P <0.01). Some AF patients with no filling of contrast media into the LAA and/or thrombus showed a larger value than the others. The value obtained by the flow-mode study might have the potential to assess blood stasis and to predict the jeopardized state in the LAA.Correspondence to: T. Nakanishi |
| Keywords: | Electron beam CT Atrial fibrillation Left atrial appendage Flow dynamics |
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