《胃癌预防的策略之一:根除幽门螺杆菌》解析

目的了解上海市某郊县体检人群开展幽门螺杆菌(Helicobacter pylori，Hp)感染流行现况。方法于2016年9~12月份，共调查3 258例参加体检的40岁及以上居民，利用免疫胶体金法对上述人群进行Hp感染的血清学筛查，并开展问卷调查，估计当地居民的Hp感染率。结果该郊县调查人群Hp总感染率为28.0%(95%CI:26.5%~29.5%)。其中, 男性为31.5%(95%CI:29.1%~33.9%)，女性为25.2%(95%CI:23.2%~27.2%)；年龄70岁及以上人群的Hp感染率最低，为24.1%(95%CI:20.9%~27.2%)；吸烟者Hp感染率为35.4%(95%CI:32.2~38.7)，非吸烟者为25.3%(95%CI:23.6~27.1)；饮酒者Hp感染率为32.3%(95%CI:28.9~35.7)，非饮酒者为27.0%(95%CI:25.3~28.8)。不同性别、不同年龄、吸烟者与非吸烟者、饮酒者与非饮酒者的Hp感染率差异均有统计学意义。结论本次调查郊县人群的Hp总感染率略低于其他地区，男性、吸烟、饮酒及年龄50岁以下人群的Hp感染率较高。

Relationship between lifetime alcohol consumption and Helicobacter pylori infection

ObjectiveTo investigate Helicobacter pylori infection situation in Shanghai suburb residents through epidemiological survey.MethodsAged 40 or above 3 258 participants receiving physical examination were selected between Sep.2016 and Dec.2016.Serological analyzed blood samples by dot immunochromatographic assay and a questionnaire survey were conducted.ResultsThe infection rate in Shanghai suburb residents was 28.0%(95%CI:26.5%-29.5%).The male rate was 31.5%(95%CI:29.1%-33.9%) and the female rate 25.2%(95%CI:23.2%-27.2%), which had significant difference.The lowest infection rate was 24.1% (95%CI:20.9%-27.2%) in the age group of older than 70 years old with significant differences among various age.The infection rates of smokers and non-smokers were 35.4% (95%CI:32.2-38.7) and 25.3%(95%CI:23.6-27.1) respectively.The infection rates of drinkers and non-drinkers were 32.3%(95%CI:28.9-35.7) and 27.0%(95%CI:25.3-28.8) respectively.The differences were all significant above.ConclusionThe infection rate of H.pylori in Shanghai suburb residents is related with sex, age, smoke and alcohol.