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Risks and possibilities in patch testing with contaminated personal objects: usefulness of thin-layer chromatograms in a patient with acrylate contact allergy from a chemical burn
Authors:Isaksson Marléne  Zimerson Erik
Affiliation:Department of Occupational and Environmental Dermatology, University Hospital MAS, Lund University, Malm? SE 205 02, Sweden. marlene.isaksson@skane.se
Abstract:We report a case of a chemical burn from dipropylene glycol diacrylate (DPGDA) spilt on working shoes, followed by active sensitization, thus giving an occupational allergic contact dermatitis on the patient's dorsal feet. Diagnostic tests included patch testing with acetone extracts made from the different shoe layers and thin-layer chromatograms. An invisible spot on the thin-layer chromatography plate gave a test eczema and was further investigated with gas chromatography-mass spectrometry. DPGDA was detected in the spot.
Keywords:chemical burn    contamination    diethylene glycol diacrylate (CAS 4074-88-8)    dipropylene glycol diacrylate (CAS 57472-68-1)    extracts    2-hydroxypropyl acrylate (CAS 2918-23-2)    N-isobutoxymethylacrylamide, occupational    shoe    thin-layer chromatography patch testing    triethylene glycol diacrylate (CAS 1680-21-3)    tripropylene glycol diacrylate (CAS 42978-66-5)
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