Orbital extra-medullary granulocytic sarcoma: clinicopathologic correlation with immunohistochemical features |
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| Authors: | Ekta Aggarwal Kaustubh Mulay Santosh G. Honavar |
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| Affiliation: | 1. Department of Oculoplastics and Ocular Oncology, Vasan Eye Care and L.V. Prasad Eye Institute, Hyderabad, India;2. National Reporting Centre for Ophthalmic Pathology, Centre for Sight, Hyderabad and Department of Ophthalmic Pathology, L.V. Prasad Eye Institute, Hyderabad, India;3. Department of Oculoplasty and Ocular Oncology, Centre for Sight, Hyderabad, and L.V. Prasad Eye Institute, Hyderabad, India |
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| Abstract: | Orbital granulocytic sarcoma (chloroma), a rare tumor of immature myeloid cells, has nonspecific clinical and radiological features that make it a diagnostic challenge. Light microscopy and confirmation by immunostaining aid in the diagnosis. Knowledge of this entity is important because early diagnosis and prompt treatment are associated with better prognosis. We report a series of 31 biopsy-proven orbital granulocytic sarcomas with their immunohistochemical features and review the literature. |
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| Keywords: | granulocytic sarcoma chloroma orbit extramedullary leukemia |
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