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妊娠期肝内胆汁淤积症合并乙型肝炎病毒感染对母婴结局的影响
引用本文:张文杰,雷菊玲,邱洪涛,张春利. 妊娠期肝内胆汁淤积症合并乙型肝炎病毒感染对母婴结局的影响[J]. 中国优生与遗传杂志, 2008, 16(10)
作者姓名:张文杰  雷菊玲  邱洪涛  张春利
作者单位:陕西省妇幼保健院产一科
摘    要:目的探讨妊娠期肝内胆汁淤积症(ICP)合并乙型肝炎病毒感染的妊娠结局。方法回顾性总结2006年1月-2007年12月陕西省妇幼保健院86例ICP合并乙型肝炎病毒感染者(研究组),同期住院治疗的单纯ICP孕妇118例(对照组)的妊娠结局,比较两组的早产率、新生儿窒息率、产后出血率等并发症的发生情况。结果妊娠期肝内胆汁淤积症合并乙型肝炎病毒感染各并发症的发生情况:早产76例、妊娠期高血压疾病17例、产后出血8例。与对照组并发症的发生差异有显著性(P<0.05)。结论妊娠期肝内胆汁淤积症合并乙型肝炎病毒感染对母婴结局产生更严重的影响。加强母婴监护,药物治疗同时适时终止妊娠可有效改善妊娠结局。

关 键 词:妊娠期肝内胆汁淤积症  乙型病毒肝炎  妊娠结局

The influence of HBV infection on the pregnancy outcome in patients with intrahepatic cholestasis
ZHANG Wen-jie,LEI Ju-ling,QIU Hong-tao,ZHANG Chun-li. The influence of HBV infection on the pregnancy outcome in patients with intrahepatic cholestasis[J]. Chinese Journal of Birth Health & Heredity, 2008, 16(10)
Authors:ZHANG Wen-jie  LEI Ju-ling  QIU Hong-tao  ZHANG Chun-li
Affiliation:ZHANG Wen-jie; LEI Ju-ling; QIU Hong-tao; ZHANG Chun-li.(Shanxi Maternity and Child Health Care Hospital; Xian 710003);
Abstract:Objective: To explore the influence of asymp tomatic HBV infection on the pregnancy outcome of patients with intrahepatic cholestasis.Methods:By using review investigation 86 cases of p regnant women suffered from ICP with asymp tomatic HBV infection and 118 cases of ICP without HBV infection were compared and analyzed,and the incidence and pregnancy outcome of ICP between the two group swere observed.Results: The incidence of ICP was higher in pregnant women who were infected by HBV than those without HBV ...
Keywords:Intrahepatic cholestasis pregnancy  Hepatitis B virus  Pregnancy outcome
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