| 雄黄诱导K562细胞凋亡的研究 |
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| 引用本文： | 张晨,黄世林,卢步峰.雄黄诱导K562细胞凋亡的研究[J].中国中医基础医学杂志,1999,0(3):30-31. |
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| 作者姓名： | 张晨 黄世林 卢步峰 |
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| 作者单位： | 中国人民解放军２１０医院血液病中医研究所，大连医科大学组胚教研室 |
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| 摘 要： | 目的检测雄黄诱导Ｋ５６２细胞的能力。方法应用形态学观察、ＤＮＡ电泳和流式细胞仪（ＦＣＭ）检测细胞凋亡。利用ＦＣＭ分析细胞周期并测定Ｋ５６２细胞线粒体膜ＡＰＯ２．７蛋白表达。结果雄黄可以诱导Ｋ５６２细胞产生凋亡现象，并导致Ｓ期细胞降低。结论雄黄具有诱导Ｋ５６２细胞凋亡的作用
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| 关 键 词： | 雄黄 凋亡 K_(562)细胞 |
Realgar Induces Apoptosis in K 562 Cells |
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| Zhang Chen\ Huang Shilin.Realgar Induces Apoptosis in K 562 Cells[J].Chinese Journal of Basic Medicine In Traditional Chinese Medicine,1999,0(3):30-31. |
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| Authors: | Zhang Chen\ Huang Shilin |
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| Abstract: | Objective:To investigate the apoplosis of K 562 cells induced by realgar.Methods:Apoptosis was detected by morphological observation DNA gel electrophoresis and flow cytometric cell cycle analysis.APO 2.7 expression was detected by flow cytometery.Results: Realgar induced K 562 cells into sub G 1 cells and significantly decreased S phase cells.Conclusion:Realgar can induce apoptosis in K 562 cells. |
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| Keywords: | Realgar Apoptosis K 562 cell |
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