某省级结核病专科医院2009-2012年抗结核药的临床应用分析

目的:了解某省级结核病专科医院抗结核药特别是二线抗结核药的临床使用情况及趋势,为抗结核药的合理使用和规范管理提供参考。方法:采用销售金额、用药频度(DDDs)排序的方法,对2009-2012年该院抗结核药的用药情况进行分析和评价。结果:一线抗结核药在抗结核治疗中仍占主要地位,二线抗结核药的用量虽呈逐年增加的趋势,但是其比例仍小于一线抗结核药。结论:该院抗结核药临床应用基本合理,同时也反映了临床实际和结核病化疗的趋势。但对二线抗结核药物在结核病治疗中的应用仍需进一步规范化管理,有效干预。

Analysis of the Utilization of Anti-tuberculosis Drugs in a Provincial Tuberculosis Special Hospital from 2009 to 2012

OBJECTIVE： To investigate the utilization of the antituberculosis drugs, especially the secondline antituberculosis drugs, in a provincial tuberculosis special hospital to offer reference for rational use and management of these drugs. METHODS ： The utilization of the antituberculosis drugs from 2009 to 2012 was analyzed statistically by using consumption sum and DDDs as in dex. RESULTS： The firstline antituberculosis drugs were still the preferred drugs, although there was a rising tendency of the con sumption of secondline antituberculosis drugs; the ratio of secondline antituberculosis drugs was less than firstline ones. CON CLUSIONS： The utilization of antituberculosis drugs in the hospital is basically reasonable, and reflects the clinical practice and trend of tuberculosis treatment. But valid intervention should be taken in the utilization of secondline antituberculosis dru~s.