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药物抗肝纤维化研究进展
引用本文:董向前,段丽平,马岚青,梁兵,缪应雷. 药物抗肝纤维化研究进展[J]. 医学综述, 2009, 15(17): 2651-2653
作者姓名:董向前  段丽平  马岚青  梁兵  缪应雷
作者单位:昆明医学院第一附属医院消化内科,昆明,650032
摘    要:肝纤维化是肝硬化的早期阶段,是慢性肝病向肝硬化发展的必经途径,也是各种慢性肝病的共同病理过程,因此阻断肝纤维化的发生和发展对于慢性肝病的治疗和预后十分重要。所以人们对抗肝纤维化药物的研究十分重视,本文对近年来抗肝纤维化药物的研究予以综述。

关 键 词:肝纤维化  细胞因子  细胞外基质  瘦素  肝星形细胞

Advance on Anti-hepatic Fibrosis Drug
DONG Xiang-qian,DUAN Li-ping,MA Lan-qing,LIANG Bing,MIAO Ying-lei. Advance on Anti-hepatic Fibrosis Drug[J]. Medical Recapitulate, 2009, 15(17): 2651-2653
Authors:DONG Xiang-qian  DUAN Li-ping  MA Lan-qing  LIANG Bing  MIAO Ying-lei
Affiliation:. ( Department of Gastroenterology, the First Affiliated Hospital of Kunming Medical College, Kunming 650032, China)
Abstract:Hepatic fibrosis is the early stage of hepatic cirrhosis, the common pathologic process of chronic hepatic diseases and results in hepatic cirrhosis in the end. So it is very important to block the occurrence and development of hepatic fibrosis in treatment of chronic hepatic diseases and prognosis, and it is paid much attention to drug of inhibiting fibrosis of liver. This article sununarized the advances in antihepatic fibrosis drug in the past few years.
Keywords:Heoatic fibrosis  Cvtokine  Extracellular matrix  Leptin  Hepatic stellate cell
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