Case of heterotopic cervical pregnancy and total placenta accreta after artificial cycle frozen‐thawed embryo transfer |
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| Authors: | Kazuki Saito Maki Fukami Mami Miyado Ichiro Ono Keijiro Sumori |
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| Affiliation: | 1. Department of Molecular Endocrinology, National Research Institute for Child Health and Development, Tokyo, Japan;2. Department of Comprehensive Reproductive Medicine, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan;3. Department of Obstetrics and Gynecology, Ome Municipal General Hospital, Tokyo, Japan |
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| Abstract: | Case A 39‐year‐old woman presented with a genital hemorrhage at 5 weeks of gestation after an artificial cycle double frozen‐thawed embryo transfer. She was diagnosed with a cervical heterotopic pregnancy. Although hormone supplementation was discontinued to terminate the pregnancy at 5 weeks of gestation, the intrauterine and cervical gestational sacs continued to develop. Outcome The cervical gestational sac was surgically removed and the intrauterine pregnancy continued uneventfully, except for vasa previa. At 36 weeks of gestation, the patient underwent a cesarean section and gave birth to a healthy female infant. At the delivery, massive bleeding occurred and a hysterectomy was performed due to total placenta accreta. Conclusion This case provides a novel example of a near‐term delivery after a cervical heterotopic pregnancy and emphasizes the need for intensive care, even after the successful management of a cervical pregnancy. Most importantly, the present case implies a possible link between hormonal withdrawal and abnormal placentation. |
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| Keywords: | artificial cycle cervical heterotopic pregnancy frozen‐thawed embryo transfer placenta accreta progesterone |
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