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Two cases of reversible male infertility due to congenital adrenal hyperplasia combined with testicular adrenal rest tumor
Authors:Mikito Tanaka  Noritoshi Enatsu  Koji Chiba  Masato Fujisawa
Affiliation:1. Department of Urology, Kobe University Graduate School of Medicine, Kobe City, Japan;2. Division of Urology, Kobe City Medical Center West Hospital, Kobe City, Japan
Abstract:

Cases

Testicular adrenal rest tumor (TART) is one of the possible causes of male infertility, accompanied by congenital adrenal hyperplasia (CAH). Here are reported two cases of TARTs that were referred to Kobe City Medical Center West Hospital for the treatment of infertility and testicular tumors.

Outcome

In one case, the semen analysis was improved from oligoasthenozoospermia to normozoospermia after taking oral glucocorticoid supplementation. The other case of original azoospermia showed that sperm had ejaculated into the semen after taking oral glucocorticoid supplementation.

Conclusion

Although the prevalence of TARTs in male infertility is very rare, it is important to know how to approach this disease, considering the curable pathology of spermatogenesis and tumors resembling an appearance to germ cell tumors.
Keywords:azoospermia  congenital adrenal hyperplasia  germ cell tumor  infertility  testicular adrenal rest tumor
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