拟调节人工晶状体在眼内位移与调节力研究

目的 探讨拟调节人工晶状体在眼内位移与调节力的关系.方法 采用病例对照研究方法,将白内障患者20例(20只眼)分成两组:10只眼植入Lestec公司生产的福来视拟调节人工晶状体(TetraflexIOL)(福来视组);另外10只眼植入其他无调节功能的人工晶状体(单焦点组).检测患者术后的裸眼远、中、近视力及矫正远、中、近视力;矫正远视力的近视力;采用前段OCT定量测定1%pilocarpine诱导缩瞳后人工晶状体在眼内前后移动的幅度;同时观察患者调节力的变化.结果 所有患者随访3个月:两组的裸眼、矫正远视力及矫正近视力差异均无统计学意义(P＞0.05);福来视组的裸眼中、近视力及矫正远视力的近视力均优于对照组(P<0.05);福来视组人工晶状体移动度及调节力与对照组比较差异有统计学意义(P<0.05),而且人工晶状体移动度与调节力呈正相关(r=0.977.P=0.000).结论 福来视拟调节人工晶状体是安伞有效的,能使患者术后获得一定的调节力,与人工晶状体的移动度具有正相关性,提供良好的远、中、近视力.

Preliminary Study of Intraoeular Movement and Accommodative Amplitude of Tetrafiex Accommodative Intraocular Lens

Objective To evaluate the relationship between the axial movement and accommodative amplitude of Tetraflex accommodative intraocular lens (Lenstec, Inc., St. Petersburg, FL). Methods Prospective case-control study comprised 20 eyes of 20 patients with age-related cataract who underwent phacoemulsification performed by a single surgeon, 10 of which were implanted with Tetraflex IOLs (Tetraflex group) and the other 10 were implanted with monofocal IOLs with limited accommodation capacity (monofocal group). Uncorrected and best corrected distance, intermediate and near visual acuity, and distance corrected near visual acuity were recorded. The axial movement of the IOL upon the application of 1% pilocarpine eye drops was obtained by anterior segment optical coherence tomography (AS-OCT), and accommodation amplitude was also measured. Results At 3-month follow up, there was no significant difference in uncorrected and best corrected distant visual acuity and best corrected near visual acuity between the two groups (P > 0.05). While the Tetraflex group had significant better uncorrected near visual acuity, intermediate visual acuity and distance corrected near visual acuity than the monofocal group (P < 0.05). The Tetraflex group also had significant greater IOL axial movement and accommodation amplitude than the monofocal group (P < 0.05), and the IOL axial movement was positively correlated with the accommodation amplitude (r=0.977, P=0.000). Conclusions The Tetraflex IOL is a safe and effective way for restoring some level of accommodation, and the amplitude of accommodation is associated with the axial movement of IOL. Tetraflex can provide good distant, intermediate and near visual acuity.