肝门部胆管癌手术治疗:附64例 报告

目的:探讨肝门部胆管癌手术方式。方法 : 回顾性分析15年间我院收治的64例肝门部胆管癌的临床资料，包括临床表现、临床分型、手术方式及治疗效果。其中35例行手术切除，包括根治性切除16例，姑息性切除19例;29例行胆管引流术，包括胆肠内引流术16例，胆管外引流术13例。结果 : 根治性切除组1，2，3年生存率分别是80.0% , 53.3%及26.7% ;姑息切除组1, 2, 3年生存率分别为50.0%, 16.7%, 0%;胆肠内引流组1,2年生存率分别是45.5%和18.2% ;外引流组则为25.0%和0 。结论:手术切除特别是根治性切除治疗是提高肝门部胆管癌疗效和提高远期生存率可选择的方法。

Surgical treatment of hilar cholangiocarcinoma: a report of 64 cases

Objective To evaluate the surgical therapy for patients with hilar cholangiocarcinoma. Methods The clinical data, including clinical manifestation, clinical stage, operative approaches and results of the treatments, of 64 patients with hilar cholangiocarcinoma treated during 16 years were retrospectively analyzed. Of the 64 patients, 35cases underwent tumor resection (radical resection in 16cases, palliative resection in 19cases), and 29 patients underwent bile duct drainage operations (internal drainage in 16cases and external drainage in 13cases). Results In the radical resection group, the 1-, 2-and 3-year survival rate was 80.0%, 53.3% and 26.7%,respectively; in the palliative resection group, the 1-, 2-and 3-year survival rate was 50.0%, 16.7% and 0%, respectively. In the internal drainage group, the 1-and 2-year survival rate was 45.5% and 18.2%, respectively; in the external drainage group, the 1-and 2-year survival rate was 25.0% and 0%, respectively. Conclusions Surgical resection, especially radical resection, can improve the therapeutic results and prolong the survival time of patients with hilar cholangiocarcinoma.