Eosinophiluria from intra-articular hyaluronic acid injection

A 68-year-old male with ischemic heart disease, mild renal impairment, and heart failure was subjected to intra-articular hyaluronic acid treatment by injection for his osteoarthritis. This was followed by worsening renal function associated with eosinophiluria but without any other systemic features of allergy. These urinary abnormalities resolved and the renal functions improved to almost baseline levels after further injections were stopped. Received: October 11, 2001 / Accepted: August 9, 2002 Correspondence to:M. Banerjee