模拟雄性大鼠老龄骨质疏松力学性质实验研究

研究了正常与老龄骨质疏松(雄性)大鼠骨的力学性质.选用280～360g、5～6个月龄Wistar雄性大鼠40只,随机分为正常对照组20只,骨质疏松模型组20只.对模型组大鼠于0周摘除睾丸,对照组与模型组大鼠饲养14周后,以腹主动脉放血法处死大鼠.取大鼠肱骨进行拉伸、压缩实验,取大鼠股骨进行弯曲、剪切实验,取大鼠胫骨进行扭转、冲击实验.大鼠肱骨拉伸、压缩最大载荷、最大应力、最大位移、最大应变及弹性模量,得出了正常对照组和模型组大鼠股骨三点弯曲最大载荷、最大弯矩、最大应力、弹性模量及剪切最大载荷、最大应力,得出了正常对照组和模型组大鼠胫骨扭转最大扭矩、扭转角、扭转剪应力、最大冲击功、冲击韧性指标,并对实验结果进行分析讨论.

Experimental study on the bone mechanical property of simulation male White rat with old age osteoporosis

To research the normal and old age male white rats osseous mechanical property of osteoporosis.40 wistar male white rats of 280-320g weignt and 5-6 months old are random divided into normal group 20 and model 20.Model group white rats are extirpated spermary on 0 week.After 14 weeks all white rats are breeding executed with abdominal aorta venisection.We take white rats' humerus to do stretch and compress testing,take femora to bent and shearing experiment,take shin to torsion and impulse testing.Maximum load,maximum stress,maximum displacement,maximum strain and elastic modulus of all white rats are obtained through stretching and compressing humerus testing,maximum load,maximum bending moment,maximum stress,elastic modulus of femora through three points bending testing.and maximum torque,angle of torsion,torsional shearing stress,maximal ballisstatistical analysis tic work,impact ductility indices of white rats' shin.We analyse and discuss the experimental results.