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某院280例药物不良反应分析
引用本文:余靖华,潘志强,邓冲. 某院280例药物不良反应分析[J]. 今日药学, 2012, 22(6): 359-360,364
作者姓名:余靖华  潘志强  邓冲
作者单位:南方医科大学附属南海医院,广东佛山,528000
摘    要:目的 对本院呈报给国家ADR中心的280例药物不良反应(ADR)监测报告进行分析.方法 收集2009 - 12 ~2010 - 12南海人民医院呈报给国家ADR中心的280例药物不良反应报告,对其进行综合分析.结果 ADR的发生率女性比男性高;老年人较容易发生药物不良反应;药物类型中抗生素所占比例最大(48.21%);用药途径中静脉滴注所占比例最大(71.79%);ADR发生部位中皮肤系统最多(58 93%),其次是中枢神经系统(13.21%).结论 应提高临床用药的安全性和合理性,加强药品不良反应的预防和监控.

关 键 词:药物不良反应(ADR)  监测

Analysis of 280 Cases of Adverse Drug Reactions in A Hospital
YU Jing-hua , PAN Zhi-qiang , DENG Chong. Analysis of 280 Cases of Adverse Drug Reactions in A Hospital[J]. Pharmacy Today, 2012, 22(6): 359-360,364
Authors:YU Jing-hua    PAN Zhi-qiang    DENG Chong
Affiliation:(The Affiliated Nanhai Hospital of Southern Medical University,Foshan,Guangdong 528000,China)
Abstract:Objective To analyze the adverse drug reaction(ADR) reports in the hospital.Methods A total of 280 cases of adverse drug reactions in our hospital in 2009-12~2010-12 that were reported to the national ADR center were collected and analyzed.Results The incidence of ADR was higher in women than men;the elderly were more prone to occur ADR;antibiotics took the largest proportion(48.21%);intravenous infusion took the largest proportion(71.79%);ADR occurred most in skin system(58.93%),followed by central nervous system(13.21%).Conclusion The clinical medication safety and rationality should be improved,and ADR report and monitoring should be strengthened.
Keywords:adverse drug reactions(ADR)  monitor
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