| 普萘洛尔在婴幼儿头颈部血管瘤中的应用 |
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| 引用本文： | 王伟财,侯劲松. 普萘洛尔在婴幼儿头颈部血管瘤中的应用[J]. 国际口腔医学杂志, 2012, 0(6): 814-817 |
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| 作者姓名： | 王伟财 侯劲松 |
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| 作者单位： | 中山大学光华口腔医学院·附属口腔医院口腔颌面外科;广东省口腔医学重点实验室 广州 510055 |
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| 基金项目： | 广东省自然科学基金资助项目（10151008901000025）;广东省科技计划基金资助项目（20098050700024,20098060700096） |
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| 摘 要： | 婴幼儿血管瘤（IH）是婴幼儿常见的良性肿瘤之一，60％发生于头颈部。IH具有自限性，但是仍有10％的婴幼儿需要治疗。目前临床上常用的治疗方法包括激素治疗、干扰素治疗、硬化治疗、激光治疗等，但均存在一定不足或不良反应。近来，普萘洛尔被证明对增生期血管瘤具有明显的消退作用。本文就普萘洛尔治疗血管瘤的分子机制、临床应用、不良反应等相关问题进行简要综述。
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| 关 键 词： | 普萘洛尔 婴幼儿血管瘤 头颈部 |
Treatment of infantile haemangioma in the head and neck region with propranolol |
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| Affiliation: | Wang Weicai, Hou Jin-song. (Dept. of Oral and Maxillofacial Surgery, Guanghua School of Stomatology, Hospital of Stomatolosy, Sun Yat-sen University; Guangdong Provincial Key Laboratory of Stomatology, Guanszhou 510055, China) |
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| Abstract: | Infantile haemangioma is a kind of the commonest childhood tumours and frequently occured in the head and neck region. They have a self-limiting course, but approximately 10% lesions require various treatment. Current clinical treatment include systemic or intralesional corticosteroids, vincristine, alpha-interferon, sclerotherapy, laser, or comprehensive of these therapies. Recent reports have highlighted the impressive efficacy of propranolol in treating rapidly proliferating haemangioma. This review focuses on the molecule mechanism of propranolol to treatment of haemangioma, clinical application and adverse respones. |
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| Keywords: | propranolol infantile haemangioma head and neck |
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