| 变异链球菌脂磷壁酸的生物学效应 |
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| 引用本文： | 张娅,于丹妮. 变异链球菌脂磷壁酸的生物学效应[J]. 国际口腔医学杂志, 2012, 0(6): 742-745 |
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| 作者姓名： | 张娅 于丹妮 |
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| 作者单位： | 天津医科大学第二医院口腔科 天津 300211 |
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| 摘 要： | 脂磷壁酸是变异链球菌的毒力因子，在变异链球菌致龋过程中发挥着重要作用，在龋病进展过程中诱导牙髓免疫应答。本文就变异链球菌脂磷壁酸的结构和功能，脂磷壁酸在牙周病进展、补体激活、细胞因子产生和牙髓细胞程序性死亡等方面的生物学效应的研究进展作一综述。
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| 关 键 词： | 变异链球菌 脂磷壁酸 生物学效应 |
Biological effects of lipoteichoic acid from Streptococcus mutans |
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| Affiliation: | Zhang Ya, Yu Donni. (Dept. of Stomatology, The Second Hospital of Tianjin Medical University, Tianjin 300211, China) |
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| Abstract: | Lipoteichoic acid, the virulence factor of Streptococcus mutans （S.mutans）, plays an important role in dental caries caused by S.mutans and induces dental pulp immune response during the advances in dental caries. Research progress reviewed in this paper is the biological effects of lipoteichoic acid from S.mutans, including structure and functions, periodontal disease progress, complement activation, production of cytokine, and apotosis of pulp cells. |
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| Keywords: | Streptococcus mutans lipoteichoic acid biological effects |
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