MRI动态增强在甲状腺疾病诊断中的应用

目的 用MR动态增强检查技术分析甲状腺占位性病变动态增强特点,探讨良、恶性甲状腺病变的增强模式.材料与方法 搜集手术病理证实的甲状腺占位性病变42例(男10例,女32例),其中良性病变28例,恶性肿瘤14例.术前均行MRI常规和动态增强检查,获得时间-信号强度曲线(TIC),并计算最大强化率(ERmax)及最大上升斜率(Slopemax)等参数.对TIC的Slopemax值及ERmax值进行中位数检验(两独立样本的位置检验).结果 TIC的Ⅰ型(快速上升型)曲线共21例,均为甲状腺良性病变,Ⅱ型(上升平台型)曲线9例,7例良性病变,2例滤泡样甲状腺癌,Ⅲ型(延迟上升型)曲线12例,均为甲状腺恶

Dynamic enhanced MRI in the diagnosis of thyroid disease

Objective:To analyze the dynamic enhancement features of 42 cases with thyroid lesions.Materials and Methods:Forty-two patients(32 women and 10 men,28 benign and 14 malignant) were included in this prospectively study.Thyroid lesions were prospectively included and underwent DCE MRI before surgery and biopsy.The time-intensity curve(TIC),maximum enhancement ratio(ER max) and the maximum rise slope(Slope max) were generated using post-processing Functool software.The median test(2 independent-samples location test) was analyzed by using statistical software SPSS 12.0.Results:All of the 21 cases with I-type curve(rapid increase) were benign thyroid.In 9 cases of II-type curve(platform type),7 cases were benign lesions and 2 cases were follicular thyroid cancer.All of the 12 cases with III-type curve(delayed up) were malignant lesions.There were significant difference(χ 2 =4.66,P=0.03) between Slope max of thyroid carcinoma(median 0.72%/s) and Slope max of benign lesions(median 4.58%/s).There were significant difference(χ 2 =4.66,P=0.03) between ER max of thyroid carcinoma(median 82.82%) and ER max of benign lesions(median 57.72%).Conclusion:(1) Dynamic contrast-enhanced MR imaging helps to differentiate benign thyroid lesions from and malignant ones.(2) Thyroid carcinoma shows delayed rise in time-intensity curve with dynamic contrast-enhanced MR imaging.Benign thyroid lesions shows rapid increase in time-intensity curve with dynamic contrast-enhanced MR imaging.