| 变异链球菌防治药物的研究现状 |
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| 引用本文： | 刘开云,孙红武,张卫军. 变异链球菌防治药物的研究现状[J]. 国际口腔医学杂志, 2012, 39(5): 683-685 |
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| 作者姓名： | 刘开云 孙红武 张卫军 |
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| 作者单位： | 国家免疫生物制品技术工程研究中心暨第三军医大学药学院微生物与生物化学药学教研室,重庆,400038 |
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| 基金项目： | 重庆市科技攻关计划基金，中国人民解放军第三军医大学科技成果转化基金 |
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| 摘 要： | 变异链球菌是人类主要的致龋微生物,其在口腔中的定植与龋病的发生密切相关。国内外学者多年来一直致力于寻找和研究抑制或杀灭变异链球菌的药物,曾运用抗生素、消毒剂、氟化物和免疫制剂等抗变异链球菌感染。本文就抗变异链球菌化学合成药物和抗变异链球菌植物提取物等研究进展作一综述。
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| 关 键 词： | 变异链球菌 龋病 药物 预防 治疗 |
Research progress on drug prevention of Streptococcus mutants |
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| Liu Kaiyun , Sun Hongwu , Zhang Weijun. Research progress on drug prevention of Streptococcus mutants[J]. Journal of International Stomatology, 2012, 39(5): 683-685 |
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| Authors: | Liu Kaiyun Sun Hongwu Zhang Weijun |
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| Affiliation: | .(National Engineering Research Center for Immunological Products and Department of Microbial and Biochemical Pharmacy,School of Pharmacy,The Third Military Medical University,Chongqing 400038,China) |
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| Abstract: | Streptococcus mutans colonization in the oral cavity is closely related to the incidence of dental caries.It is the main cariogenic micro-organisms to human.Domestic and foreign scholars,who engaged in finding and research to inhibit or kill Streptococcus mutans drugs,used the agents of antibiotics,disinfectants,fluoride and immune products to anti-Streptococcus mutans infection.Chemistry of synthetic and plant extract drugs antiStreptococcus mutans drugs reviewed in the paper. |
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| Keywords: | Streptococcus mutans dental caries drug prophylaxis treatment |
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