Active,but not passive cigarette smoking was inversely associated with mammographic density |
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| Authors: | Lesley M. Butler,Ellen B. Gold,Shannon M. Conroy,Carolyn J. Crandall,Gail A. Greendale,Nina Oestreicher,Charles P. Quesenberry Suffix" >Jr.,Laurel A. Habel |
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| Affiliation: | (1) Department of Environmental and Radiological Health Sciences, Colorado State University, 1681 Campus Delivery, Fort Collins, CO 80523-1681, USA;(2) Department of Public Health Sciences, University of California, Davis, CA, USA;(3) Division of General Internal Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA;(4) Division of Geriatrics, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA;(5) Genentech, Inc., South San Francisco, CA, USA;(6) Division of Research, Kaiser Permanente Medical Care Program, Oakland, CA, USA |
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| Abstract: | Purpose The opposing carcinogenic and antiestrogenic properties of tobacco smoke may explain why epidemiologic studies have not consistently reported positive associations for active smoking and breast cancer risk. A negative relation between mammographic density, a strong breast cancer risk factor, and active smoking would lend support for an antiestrogenic mechanism. |
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