| 福建地区汉族人群甘露糖结合蛋白基因多态性 |
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| 引用本文： | 高建平,郑瑞丹,朱青川,林震群,洪伍华,李庆端,陈哲,蔡秀珍. 福建地区汉族人群甘露糖结合蛋白基因多态性[J]. 中国优生与遗传杂志, 2011, 0(3): 18-19 |
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| 作者姓名： | 高建平 郑瑞丹 朱青川 林震群 洪伍华 李庆端 陈哲 蔡秀珍 |
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| 作者单位： | 福建省漳州市中医院;福建省漳州市175医院; |
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| 摘 要： | 目的探讨福建地区汉族人群甘露糖结合蛋白（MBP）基因多态性分布规律。方法应用聚合酶链反应-限制性内切酶片段长度多态性方法,对152例福建地区汉族健康人MBP基因第54号密码子多态性进行检测,并与其它人群比较。结果 MBP基因第54号密码子基因型频率为：GGC/GGC（71.1%）,GGC/GAC（28.9%）,GAC/GAC（0.0%）;等位基因频率为：GGC（85.5%）,GAC（14.5%）。结论福建地区汉族人群MBP基因多态分布与中国汉族、蒙古族、藏族、彝族和香港华人接近;与北欧人群和东欧人群显著不同。
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| 关 键 词： | 甘露糖结合蛋白 遗传多态性 聚合酶链反应-限制性片段长度多态性 |
Mannose binding protein (MBP) genetic polymorphisms in Fujian Hans |
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| GAO Jian-ping,ZHENG Rui-dan,ZHU Qing-chuan,LIN Zhen-qun,HONG Wu-hua,LI Qing-duan,CHEN-Zhe,CAI Xiu-zhen.. Mannose binding protein (MBP) genetic polymorphisms in Fujian Hans[J]. Chinese Journal of Birth Health & Heredity, 2011, 0(3): 18-19 |
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| Authors: | GAO Jian-ping ZHENG Rui-dan ZHU Qing-chuan LIN Zhen-qun HONG Wu-hua LI Qing-duan CHEN-Zhe CAI Xiu-zhen. |
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| Affiliation: | GAO Jian-ping,ZHENG Rui-dan,ZHU Qing-chuan,LIN Zhen-qun,HONG Wu-hua,LI Qing-duan,CHEN-Zhe,CAI Xiu-zhen.(1.Department of Gastroenterlogy,Chinese Traditional Medicine Hospital in ZhangZhou,Fujian Province,Zhangzhou 363000,China,2.175 Hospital in ZhangZhou,China) |
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| Abstract: | Objective:To determine the distribution of mannose binding protein(MBP) genetic polymorphisms in Fujian Hans.Methods:The codon 54 polymorphisms of MBP gene in a total of 152 healthy Fujian Hans were studied with Polymerase chain reaction and restrictive fragment length polymorphisrn(PCR-RFLP).Current results were compared with the data on other ethnic groups.Results:The genotype frequencies of MBP gene codon 54 was found to be GGC/GGC(71.1%),GGC/GAC(28.9%),GAC/GAC(0.0%) respectively,while the alleles geneti... |
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| Keywords: | Mannose-binding protein Genetic polymorphism PCR-RFLP |
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