芪连液保留灌肠治疗婴幼儿秋季腹泻临床及实验研究

目的：研究治疗婴幼儿秋季腹泻的有效方法。方法：选择大便标本轮状病毒抗原阳性的腹泻患儿行芪连液保留灌肠，同时与对照组对比观察临床疗效、轮状病毒转阴、血清免疫球蛋白（Ｉｇ）等，并进行动物实验研究。结果：治疗组治疗后主要症状消失时间，轮状病毒转阴率，血清ＩｇＡ、ＩｇＧ水平较对照组明显升高（Ｐ〈０．０１，Ｐ〈０．０５）；实验研究表明芪连液不仅具有抗病毒止泻作用，还有提高机体免疫功能，保护肠粘膜作用。结论：

Clinical and Experimental Study on Treatment of Infantile Autumn Diarrhea by Retention Enema with Qilian Liquid

To find out the effective treatment for infantile autumn diarrhea (IAD). Methods: Retention enema with Qilian Liquid (QLL) was applied to the patients of IAD with positive antigen of rotavirus in stool, and the clinical effect in the treated group was compared with that in the control group in aspects of negative conversion rate of rotavirus and change of immnoglobulin. Animal experimental study was also conducted. Results: The disappearance time of principal symptoms, negative conversion rate of rotavirus and serum levels of IgA and IgG in the treated group were significantly higher than those in the control group (P<0 01, P<0 05). Experimental study showed that QLL not only has the the anti-viral effects to stop diarrhea, but also has effects in enhancing immune function and protecting intestinal mucous membrane. Conclusion: Retention enema with QLL is an effective therapy for the treatment of IAD.