Researches on antiinflammatory agents. Studies on some new 3-(pyrazol-5-yl)-1,2,3-benzotriazin-4(3H)-ones and -quinazolin-4(3H)-ones |
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| Authors: | G Daidone S Plescia D Raffa M L Bajardi M Matera A Caruso M G Leone |
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| Institution: | Dipartimento di Chimica e Technologie Farmaceutiche, Università di Palermo. |
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| Abstract: | Following our research on analgesic and antiinflammatory active compounds containing the pyrazole nucleus, a number of 3-(pyrazol-5-yl)-1,2,3-benzotriazin-4(3H)-ones and quinazolin-4(3H)-ones was synthetized and tested. The results of tests for analgesic, antiexudative and antioedema activities, as well as for induction of lesion in the gastric mucosa, are reported and discussed. |
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