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IMMUNOLOGICAL CLASSIFICATION OF ACUTE LYMPHOBLASTIC LEUKEMIA
Authors:Y Bai  Z X Tan  D F Zhang
Abstract:112 cases of acute Iymphoblastic Ieukemia (ALL) wcre subtyped by cell surface markers and a paneil of monoclonal antibodies. All 4 major groups were found: common ALL (C-ALL), NulI.ALL, T cell type ALL (T-ALL) and B cell type ALL (B-ALL). Morpho-- logical classification and immunological subtyping were also comparcd. The percentage of different : subtypes of ALL was: C-ALL 75To, NuII.ALL 13%, T-ALL 10% and B-ALL 2%. ALL prevalence was observed among children aged l-5 years. Male prc dominancc was noted. T-ALL patients had highest average WBC counts and a high percentage of severe lymphocytosis. Immunological classification seems to improve precision of diagnosis.
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