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Sarcomatoid chordoma: chordoma with a massive malignant spindle-cell component |
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| Authors: | Yosuke Morimitsu Takatoshi Aoki Koichiro Yokoyama H Hashimoto |
| Institution: | (1) Department of Pathology and Oncology, School of Medicine, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu-shi 807-8555, Japan, JP;(2) Department of Radiology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan, JP;(3) Department of Orthopedics, National Kokura Hospital, Kitakyushu, Japan, JP |
| Abstract: | We report a case of chordoma containing a spindle cell sarcomatoid component with a gradual transition from conventional chordoma. Immunohistochemically, many tumor cells in both conventional chordoma and sarcomatoid components were positive for cytokeratins (AE1/AE3, CAM5.2) and epithelial membrane antigen as well as vimentin. This report provides a rare example of sarcomatoid chordoma. Familiarity with this type of bone tumor should help to avoid confusion with dedifferentiated chordoma and other spindle cell sarcomas or carcinomas. Received: 25 February 2000 Revision requested: 28 March 2000 Revision received: 30 May 2000 Accepted: 28 June 2000 |
| Keywords: | Chordoma Sarcomatoid chordoma Transitional feature Sacrum CT MRI |
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