经尿道前列腺切除治疗晚期前列腺癌下尿路梗阻

目的 :观察经尿道前列腺电切除术 (TURP)在治疗晚期前列腺癌相关的下尿路梗阻中的意义。　方法 :回顾性分析 2 0 0 2年 5月～ 2 0 0 3年 11月在我院接受TURP的 2 6例前列腺癌患者病史资料。　结果 :2 6例患者 ,年龄 5 6～92岁 ,中位年龄 75岁。C期 3例 ,D期 2 3例。 9例患者有尿潴留病史 ,其中 1例肾功能不全 ,膀胱造瘘 1个月后行TURP。 2 6例患者术中出血量不多 ,无 1例术中输血。术后 3～ 5d拔除导尿管后均可自行排尿 ,但并发暂时性尿失禁3例 ,经提肛肌练习后恢复正常。 9例曾有尿潴留病史的患者无 1例再次发生尿潴留 ,术后 8周国际前列腺症状评分(IPSS)和一般状况评分 (Karnofsky)均明显改善 [分别为 (2 9.7± 4 .6 )vs (8.6± 3.4 )、(5 5± 2 0 )vs (77± 32 )分 ,P均 <0 .0 5 ]。　结论 :TURP治疗前列腺癌相关的下尿路梗阻安全有效。

Transurethral Resection of the the Prostate for Lower Urinary Tract Obstruction from Advanced Prostate Cancer

OBJECTIVE: To investigate the role of transurethral resection of the prostate (TURP) in the treatment of lower urinary tract obstruction due to advanced prostate cancer. METHODS: A retrospective analysis was made of the clinical materials of 26 patients with advanced prostate cancer treated by TURP from May, 2002 to November, 2003. RESULTS: Of the 26 patients, aged 56 - 92 years (75 on average), 3 were at Stage C and 23 at Stage D, and 9 had a history of urine retention, of whom 1 with renal function insufficiency received TURP after 1 month suprapubic drainage. There was little blood loss and no need for blood transfusion. Incontinence was temporary and no retention occurred after surgery. The international prostate symptom score (IPSS) and Karnofsky score improved significantly (29.7 +/- 4.6 versus 8.6 +/- 3.4 and 55 +/- 20 versus 77 +/- 32 respectively, P < 0.05). CONCLUSION: TURP is a safe and efficient therapeutic option to relieve lower urinary tract obstruction due to advanced prostate cancer.