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Utility of Early Insulin Response and Proinsulin to Assess Insulin Resistance

Authors:	Amy M Jean Abeer Hassoun Jennifer Hughes Ilene Fennoy Donald J McMahon Sharon E Oberfield

Institution:	^a Department of Pediatrics, Division of Pediatric Endocrinology, Columbia University, New York, NY ^b Department of Medicine, Division of Endocrinology, Columbia University, New York, NY

Abstract:

Keywords:	Δ4-A Δ4-androstenedione AN Acanthosis nigricans BMI Body mass index CV Coefficient of variation DHEAS Dehydroepiandrosterone sulfate EIR Early insulin response FGIR Fasting glucose to insulin ratio FSH Follicle-stimulating hormone GCRC General Clinical Research Center HDL High-density lipoprotein HOMA Homeostasis Model Assessment IFG Impaired fasting glucose IGF-1 Insulin-like growth factor 1 IGFBP-1 Insulin-like growth factor binding protein 1 IGT Impaired glucose tolerance ISI(comp) Composite whole-body insulin sensitivity index LDL Low-density lipoprotein LH Luteinizing hormone PI Proinsulin QUICKI Quantitative insulin sensitivity check index SHBG Sex hormone-binding globulin T2DM Type 2 diabetes mellitus
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