| 黄连解毒汤提取工艺及其滴丸制备的研究 |
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| 引用本文： | 马云淑,阮志国,余华. 黄连解毒汤提取工艺及其滴丸制备的研究[J]. 中国实验方剂学杂志, 1999, 5(4): 1-3 |
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| 作者姓名： | 马云淑 阮志国 余华 |
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| 作者单位： | 云南中医学院中药系 |
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| 基金项目： | 云南省教委应用基础课题 |
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| 摘 要： | 通过采用柱层析纯化法测定小檗碱的含量，研究比较了黄连解毒汤的提取工艺流程；采用正交试验法研究了黄连解毒滴丸成型的较优工艺条件：提取物∶ＰＥＧ６０００∶水∶甘油按１∶１．８∶０．４∶０．４比例混匀，保温于（９０±２）℃的滴制装置内，用滴口内径／外径为２．５／３．５（ｍｍ）的滴管以（１０±２）Ｄ／ｍｉｎ的滴速滴入温度为室温的冷却液中。
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| 关 键 词： | 黄连解毒汤 小檗碱 滴丸 成型工艺 |
| 收稿时间： | 1998-10-26 |
Studies on Extracting Process and Pilule Preparation of Huanglianjiedu Decoction |
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| Ma Yunshu,Ruan Zhiguo,Yu Hua. Studies on Extracting Process and Pilule Preparation of Huanglianjiedu Decoction[J]. China Journal of Experimental Traditional Medical Formulae, 1999, 5(4): 1-3 |
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| Authors: | Ma Yunshu Ruan Zhiguo Yu Hua |
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| Affiliation: | Yunnan College of TCM,Yunnan,650011 |
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| Abstract: | The extracting processes of Huanglianjiedu decoction were studies by determining the content of berberine with the method of column chromatography purification. By orthogonal design test,the optimum preparation conditions for shaping the pilule were determined as: extractPEG6000waterglycerin=1180404,well mingled and kept in pilulemaking device with temperature at (902), then was dropped in a cooler (202) through a dropper (internal/external diameter=25/35mm) at a speed of(102)drops/min. |
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| Keywords: | Huanglianjiedu decoction Berberine pilule preparation procedure |
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