|
|||||
|
|
| 几种环境污染物质在体检人群中的内暴露水平 | |
| 引用本文： | 雷雅静,朱银焕,施卫星,那仁满都拉,陈枢青. 几种环境污染物质在体检人群中的内暴露水平[J]. 浙江大学学报(医学版), 2013, 42(1): 14-18 |
| 作者姓名： | 雷雅静 朱银焕 施卫星 那仁满都拉 陈枢青 |
| 作者单位： | 1.浙江大学药学院药理毒理与生化药学研究所，浙江 杭州 310058； 2.杭州爱贝亚检测技术有限公司，浙江 杭州 310051； 3.浙江大学医学院公共卫生系，浙江 杭州 310058 |
| 基金项目： | 浙江省重大科技专项基金，浙江省卫生科研基金 |
| 摘 要： | 目的：测定体检人群中几种常见环境污染物质的含量，了解这些环境污染物质在正常人群中的内暴露程度。 方法：采用GC、GC-MS、HPLC、ELISA等方法，对80例体检人群尿样中环境污染物的含量进行检测。 结果：甲醛和甲苯的检出率分别为97.6%和41.2%；黄曲霉毒素M1（aflatoxin M1,AFM1）的检出率为91.4%；邻苯二甲酸二丁酯（dibutyl phthalate,DBP）的检出率为75.3%；有机磷的检出率在1.2%～41.2%之间；三种多氯联苯（polychlorinated biphenyl,PCBs）、氯丙嗪（chlorpromazine,CPZ）和4,5-二氯儿茶酚(4,5-dichlorocatechol,4,5-DCC)的检出率较低，检出人数均少于5例；三甲基氯化锡(trimethyltin-chloride,TMT)未检出。 结论：部分环境污染物在体检人群中的内暴露程度较高，其对人体的影响和限值研究亟待加强。 |
| 关 键 词： | 环境污染物 职业暴露 尿/分析 甲醛 甲苯 黄曲霉毒素M1 酶联免疫吸附测定 色谱法,高压液相 气相色谱-质谱法 色谱法,气相 |
Determination of several environmental contaminants in human body |
|
| LEI Yajing , ZHU Yinhuan , SHI Weixing , HUA Naranmandura , CHEN Shuqing. Determination of several environmental contaminants in human body[J]. Journal of Zhejiang University. Medical sciences, 2013, 42(1): 14-18 | |
| Authors: | LEI Yajing ZHU Yinhuan SHI Weixing HUA Naranmandura CHEN Shuqing |
| Affiliation: | 1.Institute of Pharmacology,Toxicology and Biochemical Pharmaceutics.College of Pharmaceutical Sciences,Zhejiang University,Hangzhou 310058,China; 2.Hangzhou EPIE Bio-detection Technology Limited,Hangzhou 310051,China; 3.Institute of Public Health，Zhejiang University School of Medicine,Hangzhou 310058,China |
| Abstract: | Objective： To detect common environmental pollutants in human body. Methods： Urine samples were collected from 80 healthy subjects.Chromatography mass spectrometry (GC-MS),HPLC and ELISA were applied to detect several common environmental pollutants in urine samples. Results： DBP and methylbenzene were present in 75.3% and 41.2% of urine samples.The methanal and AFM1 were found in most of urine samples (approximately 91~97%).By contrast,PCBs,CPZ,4,5-DCC were found in less than 5 samples,but there was no TMT detected. Conclusion： Some of the environmental pollutants including carcinogens are detected in urine samples in this study. |
| Keywords: | |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |
| 点击此处可从《浙江大学学报(医学版)》浏览原始摘要信息 | |
| 点击此处可从《浙江大学学报(医学版)》下载全文 | |