血清降钙素原在老年肺炎临床诊断与治疗中的应用价值探讨

目的：探讨血清降钙素原在老年肺炎患者诊断和治疗中的价值。方法方便选取2013年6月—2015年6月该院110例老年肺炎患者作为实验组,按严重程度分为低、中、高3组,同时选取60例非感染性支气管疾病作为对照组,对治疗前后血清PCT及CRP水平进行对比分析。结果治疗前实验组患者PCT(10.05±2.57)及CRP(51.06±5.94)水平均高于对照组(0.97±0.38,3.96±0.87),差异有统计学意义(P<0.05)；治疗1周后低危组和中危组PCT水平显著下降,差异有统计学意义(P<0.05),CRP水平较治疗前相比差异无统计学意义(P>0.05)。结论血清降钙素原可作为诊断和治疗老年肺炎的新型炎症标志物,能够准确评价临床预后及抗感染治疗效果。

Observation on Application Value of Serum Procalcitonin in Clinical Diag-nosis and Treatment of Senile Pneumonia

Objective To study the value of serum procalcitonin in clinical diagnosis and treatment of senile pneumonia. Methods 110 cases of patients with senile pneumonia treated in our hospital from June 2013 to June 2015 were selected as the experimental group, and divided into the low-risk, moderate-risk and high-risk groups according to the severity, at the same time, 60 cases of patients with non-infectious bronchial disease were selected as the control group, and the serum PCT and CRP levels before and after treatment were compared and analyzed. Results The PCT and CRP levels in the ex-perimental group before treatment were higher than those in the control group with statistical significance, [(10.05 ±2.57), (51.06±5.94) vs (0.97±0.38), (3.96±0.87)], P<0.05; the PCT levels in the low-risk group and moderate-risk group after 1 week of treatment obviously decreased with statistical significance, P<0.05, but there was no statistical difference in the CRP level compared with that before treatment, P>0.05. Conclusion Serum procalcitonin can be used as the new type of inflammation marker, and it can accurately evaluate clinical prognosis and anti-infectious treatment effect.