前列地尔注射液联合银杏达莫注射液治疗糖尿病下肢血管病变患者的临床疗效

目的：探讨前列地尔注射液联合银杏达莫注射液治疗糖尿病下肢血管病变患者的临床疗效以及应用价值。方法整群选取2014年4月-2015年4月在该院治疗的糖尿病下肢血管病变患者190例,根据随机数字表将患者分为实验组(n=95﹚和对照组(n=95﹚,实验组患者予以前列地尔注射液联合银杏达莫注射液的治疗方法,对照组予以银杏达莫注射液的治疗方法,1个疗程后观察两组患者的恢复情况和疗效时间。结果实验组患者治愈41例(43.2%﹚,好转35例(36.8%﹚,无效19例(20.0%﹚,总有效76例(80.0%﹚；对照组患者治愈27例(28.4%﹚,好转18例(18.9%﹚,无效50例(52.7%﹚,总有效45例(47.3%﹚。实验组患者的显效时间为(26.1±3.2)d,对照组为(34.7±1.4)d；实验组的有效时间为(22.5±2.3)d,则对照组为(27.4±1.8)d。实验组患者的恢复情况和治疗所需时间均优于对照组,两组比较差异均具有统计学意义(P<0.05﹚。结论前列地尔注射液联合银杏达莫注射液在糖尿病下肢血管病变患者临床疗效显著,安全有效并无严重的不良反应,值得在临床上使用以及推广。

Clinical Curative Effect of Alprostadil Injection Combined with Ginkgo Dipyridolum Injection in Treatment of Patients with Lower-Extremity Ar-terial Disease in Diabetes

Objective To discuss the clinical curative effect and application value of alprostadil injection combined with inkgo dipyridolum injection in treatment of patients with lower-extremity arterial disease in diabetes. Methods 190 cases of patients with lower-extremity arterial disease in diabetes treated in our hospital from April 2014 to April 2015 were se-lected and randomly divided into two groups with 95 cases in each, the experimental group were treated with alprostadil in-jection combined with ginkgo dipyridolum injection, the control group were treated with ginkgo dipyridolum injection, the recovery condition and curative effect time of the two groups after 1 course of treatment were observed. Results In the ex-perimental group, 41 cases were healed (43.2%﹚, 35 cases were improved (36.8%﹚, 19 cases were ineffective (20.0%﹚, 76 cases were effective in total (80.0%﹚;in the control group, 27 cases were healed (28.4%﹚, 18 cases were improved (18.9%﹚, 50 cases were ineffective (52.7%﹚, 45 cases were effective in total (47.3%﹚, the effectual time was (26.1±3.2)d in the experimental group and (34.7±1.4)d in the control group, the effective time was (22.5±2.3)d in the experimental group and (27.4±1.8)d in the control group, the recovery condition and treatment time in the experimental group were better than those in the control group, the differences between the two groups by comparison were statistically significant (P<0.05﹚. Conclusion The alprostadil injection combined with ginkgo dipyridolum injection in treatment of patients with lower-ex-tremity arterial disease in diabetes has an obvious clinical curative effect, and it is safe and effective and there was no se-vere adverse reaction, which is worthy of application and promotion in clinic.