| 儿童急性下呼吸道感染病毒病原学分析 |
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| 引用本文： | 田曼,施圣云,秦铭,刘红霞,赵德育.儿童急性下呼吸道感染病毒病原学分析[J].临床儿科杂志,2010,28(2). |
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| 作者姓名： | 田曼 施圣云 秦铭 刘红霞 赵德育 |
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| 作者单位： | 1. 南京医科大学附属南京儿童医院呼吸科,江苏南京,210008
2. 南京医科大学附属南京儿童医院儿科研究所,江苏南京,210008 |
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| 摘 要： | 目的了解儿童急性下呼吸道感染病毒病原学特点。方法采用直接免疫荧光法(DIF),对2007年9月—2009年9月住院的5480例0～12岁下呼吸道感染患儿鼻咽分泌物进行8种病毒检测。结果5480例患儿中,2710例检出至少1种病毒,总检出率49.5%。呼吸道合胞病毒(RSV)检出最多,为1386例,占51.1%,其余,依次是偏肺病毒(hMPV)513例(18.9%),副流感病毒Ⅲ(PIVⅢ)338例(12.5%),腺病毒(ADV)192例(7.1%);流感病毒A(IFA)128例(4.7%),流感病毒B(IFB)79例(2.9%),副流感病毒Ⅰ(PIVⅠ)41例(1.5%),副流感病毒Ⅱ(PIVⅡ)33例(1.2%)。6个月以下年龄组阳性率最高,为43.5%。RSV、hMPV季节性较明显,主要集中在冬春季节(11月至次年4月)。肺炎、毛细支气管炎、支气管炎(伴喘息)、支气管炎(不伴喘息)和哮喘患儿病毒阳性率分别为47.4%、63.6%、50.5%、30.1%和43.5%。结论病毒是儿童急性下呼吸道感染的主要病原。发病年龄主要在婴幼儿,其中RSV和hMPV最常见。
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| 关 键 词： | 儿童 急性下呼吸道感染 病毒 病原学 |
Analysis of viral pathogen in children with acute lower respiratory tract infections |
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| TIAN Man,SHI Sheng-yun,QIN Min,LIU Hong-xia,ZHAO De-yu.Analysis of viral pathogen in children with acute lower respiratory tract infections[J].The Journal of Clinical Pediatrics,2010,28(2). |
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| Authors: | TIAN Man SHI Sheng-yun QIN Min LIU Hong-xia ZHAO De-yu |
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| Institution: | 1.Department of Respiratory/a>;2.Institute of Pediatrics/a>;The Affiliated Nanjing Children's Hospital of Nanjing Medical University/a>;Nanjing 210008/a>;Jiangsu/a>;China |
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| Abstract: | Objective To elucidate the etiology feature of viral infection in hospitalized children with acute lower respiratory infection.Methods A total of 5480 children with acute lower respiratory tract infection,hospitalized from September 2007 to September 2009,were studied.Nasopharyngeal aspirates were screened for 8 types of viruses by direct immunofluorescence(DIF) assay.Results At least one type of viral pathogen was detected in 2710 out of 5480 patients and the overall positive rate was 49.5%.The most common... |
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| Keywords: | children acute lower respiratory tract infection virus pathogen |
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