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Two synchronous adenocarcinomas of the small bowel in a patient with undiagnosed Crohn's disease of the terminal ileum
Authors:P. Sammartino  S. Sibio  A. Di Giorgio  R. Caronna  A. Viscido  M. Zippi  D. Biacchi  F. Accarpio  P. Mingazzini  R. Caprilli
Affiliation:(1) Dipartimento di Chirurgia P. Valdoni, University of Rome La Sapienza, Policlinico Umberto I, Via Lancisi, 2-00185 Rome, Italy;(2) Istituto Dipartimentalizzato di Chirurgia d'Urgenza e Pronto Soccorso, University of Rome La Sapienza, Policlinico Umberto I, Via Lancisi, 2-00185 Rome, Italy;(3) Dipartimento di Scienze Cliniche, University of Rome La Sapienza, Policlinico Umberto I, Via Lancisi, 2-00185 Rome, Italy;(4) Dipartimento di Medicina Sperimentale e Patologia Clinica, University of Rome La Sapienza, Policlinico Umberto I, Via Lancisi, 2-00185 Rome, Italy
Abstract:A small but significant excess of deaths for tumors of the digestive system has been described in Crohn's disease. In a study analyzing all cancers of the small intestine within a defined population, Crohn's disease was the major underlying factor for cancer of the small intestine. Areas of the small intestine containing strictures are unusually prone to malignant transformation. We report the rare case of a patient in whom surgery for intestinal occlusion disclosed Crohn's disease of the distal ileum complicated by two adenocarcinomas arising within distinct areas of the inflamed bowel.
Keywords:Crohn  Small bowel  Adenocarcinoma  Strictures
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