| 儿童深部真菌感染的治疗 |
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| 引用本文： | 黄延风,杨烈利,朱朝敏.儿童深部真菌感染的治疗[J].儿科药学杂志,2005,11(3):24-25. |
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| 作者姓名： | 黄延风 杨烈利 朱朝敏 |
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| 作者单位： | 1. 重庆医科大学附属儿童医院,重庆,400014
2. 重庆市渝北区人民医院,重庆,401120 |
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| 摘 要： | 目的：探讨儿童深部真菌感染的治疗。方法：回顾性分析14例经病原学检查确诊的儿童深部真菌感染的临床资料。结果：14例患儿中11例为新隐球菌脑膜炎，3例为新隐球茵全身感染；13例给予抗真菌治疗，其中2例单用氟康唑(F1u)，另11例用二性霉素B(AMB)或脂质体二性霉素B(L-AMB)联合氟康唑或5-氟胞嘧啶(5-FC)，3例治愈。7例好转。结论：新隐球菌是儿童深部真菌感染的常见病原，AMB联合5-FC或Flu是治疗儿童深部真菌感染的主要方案。
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| 关 键 词： | 深部真菌感染 儿童:二性霉素B |
| 文章编号： | 1672-108X(2005)03-0024-02 |
| 修稿时间： | 2005年3月25日 |
The treatment of deep fungal infections in children |
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| HUANG Yan-feng,YANG Lie-li,ZHU Chao-min.The treatment of deep fungal infections in children[J].Journal of Pediatric Pharmacy,2005,11(3):24-25. |
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| Authors: | HUANG Yan-feng YANG Lie-li ZHU Chao-min |
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| Abstract: | Objective: To investigate treatment in children with deep fungal infections (DFI). Methods: A retrospective analysis was performed on the clinical data of 14 patients with deep fungal infections. Results: Among 14 cases, there were 11 cases with cryptococcal meningitis and 3 cases with systemic cryptococcosis; 13 cases were treated with antifungal therapy, fluroconazole(Flu) was used alone in 2 cases, amphotericin B (AMB) or liposome amphotericin (L-AMB) combined with Flu or 5-FC in 11 cases, and 3 cases were cured, 7 cases were relieved. Conclusion: The main pathogenic fungal species are cryptococcus, and AMB combined with Flu or 5-FC is effective types in treating DFI. |
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| Keywords: | Deep fungal infections Child AMB |
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