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中药“维脑路通”的组成分析研究
引用本文:张昌鸣,李爱英,陈克玲.中药“维脑路通”的组成分析研究[J].药学学报,1981,16(12):925-930.
作者姓名:张昌鸣  李爱英  陈克玲
作者单位:中国科学院山西煤炭化学研究所 太原 (张昌鸣,李爱英),中国科学院山西煤炭化学研究所 太原(陈克玲)
摘    要:以高效液相色谱进行分离,配以薄层层析,紫外光谱等方法研究测定了中药“维脑路通”的组成。定性结果表明“维脑路通”的主要成分有7-羟乙基芦丁、4',7-二羟乙基芦丁、3',4',7-三羟乙基芦丁,3',4',5,7-四羟乙基芦丁等八种主要组分,用色谱法对各组分的含量作了测定。

收稿时间:1980-10-24

ANALYSIS OF THE COMPOSITION OF THE CHINESE DRUG VENORUTON
Zhang Changming,Li Aiying,and Chen Keling.ANALYSIS OF THE COMPOSITION OF THE CHINESE DRUG VENORUTON[J].Acta Pharmaceutica Sinica,1981,16(12):925-930.
Authors:Zhang Changming  Li Aiying  and Chen Keling
Abstract:The present paper describes the use of high performance liquid chromatography to separate the Chinese drug venoruton.It was separated by K-1 silica gel column and was identified by UV, HPLC and TLC.The composition was found to be mainly: 7-mono-O-(β-hydroxyethyl) rutoside (HER); 4',7-di-O-(β-hydroxyethyl) rutoside 3',7-di-O-(β-hydroxyethyl) rutoside 3',4',7-tri-O-(β-hydroxyethyl) rutoside 4', 5,7-tri-O-(β-hydroxyethyl) rutoside 3', 5,7-tri-O-(β-hydroxyethyl) rutoside and 3',4',5,7-tetra-O-(β-hydroxyethyl)rutoside.The quantitative analysis indicates that it consists of about 33% of mono-HER, 37% of di-HER, 26% of tri-HER,2% of tetra-HER and 2% of rutin.
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