Linking preclinical and clinical whole-body physiologically based pharmacokinetic models with prior distributions in <Emphasis Type="SmallCaps">NONMEM</Emphasis>期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Linking preclinical and clinical whole-body physiologically based pharmacokinetic models with prior distributions in NONMEM

Authors:	Grant Langdon Ivelina Gueorguieva Leon Aarons Mats Karlsson

Affiliation:	(1) Department of Pharmaceutical Biosciences, Division of Pharmacokinetics and Drug Therapy, Uppsala University, Uppsala, Sweden;(2) Eli Lilly & Company Ltd, Windlesham, Surrey, UK;(3) School of Pharmacy and Pharmaceutical Sciences, University of Manchester, Manchester, UK

Abstract:

Keywords:	Bayesian analysis Diazepam NONMEM Physiologically-based pharmacokinetic models Prior distributions
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