| 补益中药有效活性成分的免疫药理研究及应用 |
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| 引用本文： | 邢善田,耿长山,周金黄.补益中药有效活性成分的免疫药理研究及应用[J].军事医学科学院院刊,1988(3). |
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| 作者姓名： | 邢善田 耿长山 周金黄 |
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| 作者单位： | 军事医学科学院毒物药物研究所,军事医学科学院毒物药物研究所,军事医学科学院毒物药物研究所 |
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| 摘 要： | 几种补益中药(枸杞子、淫羊藿、黄芪和女贞子)的多糖成分具有免疫增强和调节作用,这种作用以提高T淋巴细胞功能为主.主要包括:(1)对有丝分裂剂诱导的T细胞增殖反应更敏感;(2)提高细胞免疫功能的作用部位在胸腺;(3)对于免疫功能低下的老龄鼠和荷瘤鼠均有明显增强T淋巴细胞活性作用.补益中药的多糖成分可能是它们具有"扶正固本"和调节免疫功能的主要物质基础.
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| 关 键 词： | 补益中药 多糖 免疫增强 T淋巴细胞 |
IMMUNOPHARMACOLOGICAL RESEARCH AND USAGE OF ACTIVE INGREDIENT OF TONICS IN TRADITIONAL MEDICINE |
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| Xin Shantian,Geng Changshan,Zhou Jinhuang Institute of Pharmacology and Toxicology,Academy of Military Medical Sciences.IMMUNOPHARMACOLOGICAL RESEARCH AND USAGE OF ACTIVE INGREDIENT OF TONICS IN TRADITIONAL MEDICINE[J].Bulletin of the Academy of Military Medical Sciences,1988(3). |
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| Authors: | Xin Shantian Geng Changshan Zhou Jinhuang Institute of Pharmacology and Toxicology Academy of Military Medical Sciences |
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| Abstract: | Polysaccharides from several tonics in traditional medicine (Lycium barbarum,Astragalus mongolicus,Epimedium koreanum and Ligustrum lucidum) increased and adjusted immune function.They mainly potentiated the function of T lymphocytes,including:(1)increasing the proliferation of T cells induced by ConA but not that induced by LPS,(2)increasing cellular immune function of thymus,(3)significantly potentiating the activity of T cells in old mice with decreased immune function and tumor-bearing mice.These polysaccharides may be major ingredients of tonics that restore health in debilitated conditions. |
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| Keywords: | traditional tonic medicine polysaccharide immunopotentiation T lymphocyte |
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