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| 比较基因组杂交芯片筛选头颈部鳞状细胞癌患者转移相关的差异表达基因 | |
| 引用本文： | 李雅冬,A Gowhere,洪苏玲. 比较基因组杂交芯片筛选头颈部鳞状细胞癌患者转移相关的差异表达基因[J]. 第三军医大学学报, 2011, 0(18): 1974-1976 |
| 作者姓名： | 李雅冬 A Gowhere 洪苏玲 |
| 作者单位： | 1. 重庆医科大学附属第一医院：颌面外科,重庆,400016 2. Strasbourg,France, Centre Regional de Lutte Contre le Cancer Paul Strauss,3 rue Porte de 1' Hopital 3. 重庆医科大学附属第一医院：耳鼻喉头颈外科,重庆,400016 |
| 基金项目： | 重庆医科大学校办基金(2007020)~~ |
| 摘 要： | 目的 检测头颈部鳞状细胞癌（head and neck squamous cell carcinoma，HNSCC）标本，寻找与HNSCC转移有高度相关性的基因。方法采用比较基因组杂交芯片技术，分别检测80例临床HNSCC标本，包括舌癌17例，口腔癌13例，口咽癌14例，下咽癌36例。结果比较基因组杂交CGH检测结果示... |
| 关 键 词： | 头颈部鳞状细胞癌 基因芯片 转移 |
Differential expression of metastasis-related genes in patients with head and neck squamous cell carcinoma:a genomic hybridization microarray study |
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| Li Yadong,A Gowhere,Hong Suling. Differential expression of metastasis-related genes in patients with head and neck squamous cell carcinoma:a genomic hybridization microarray study[J]. Acta Academiae Medicinae Militaris Tertiae, 2011, 0(18): 1974-1976 | |
| Authors: | Li Yadong A Gowhere Hong Suling |
| Affiliation: | Li Yadong1,A Gowhere2,Hong Suling3(1Department of Oral and Maxillofacial Surgery,3Department of Otolaryngology Head and Neck Surgery,First Affiliated Hospital,Chongqing Medical University,Chongqing,400016,China,2Centre Regional de Lutte Contre le Cancer Paul Strauss,3 rue Porte de l'Hopital,Strasbourg,France) |
| Abstract: | Objective To detect the metastasis-related genes in patients with head and neck squamous cell carcinoma(HNSCC).Methods HNSCC metastasis-related genes were detected with genomic hybridization microarray in 80 samples from HNSCC patients,including 17 from tongue cancer patients,13 from oral cancer patients,14 from oropharynx cancer patients,and 36 from hypopharynx cancer patients.Results Genomic hybridization CGH showed that significant differences were observed in gene amplification at the sites of 1q,4q,7q,... |
| Keywords: | head and neck cancer gene microarray metastasis |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |