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文拉法辛治疗冠心病患者合并焦虑抑郁的临床研究
引用本文:宋修丽,崔明湖,耿丽. 文拉法辛治疗冠心病患者合并焦虑抑郁的临床研究[J]. 滨州医学院学报, 2011, 0(4): 277-278,281
作者姓名:宋修丽  崔明湖  耿丽
作者单位:滨州医学院精神病学教研室滨州市256603;滨州医学院病原生物学教研室
摘    要:目的观察文拉法辛对冠心病合并焦虑抑郁障碍患者治疗的疗效。方法将196例冠心病患者采用Zung氏焦虑自评量表(SAS)及抑郁自评量表(SDS)评定焦虑抑郁情绪,检测出合并焦虑抑郁症者52例,将其随机分为对照组和治疗组,前者给予常规治疗,后者在常规治疗同时加用抗抑郁药物文拉法辛胶囊,治疗8周。于治疗前及治疗第8周末进行对比分析。结果治疗组在治疗第8周末SAS及SDS评分较治疗前及对照组均显著下降(P〈0.05),心绞痛、心律失常、心肌梗死及心源性猝死发生率明显降低(P〈0.05)。结论冠心病合并焦虑抑郁症患者在常规治疗同时加用文拉法辛,其疗效显著优于单纯常规治疗。

关 键 词:文拉法辛  冠心病  焦虑  抑郁

Clinical study of venlafaxine in the treatment of patients with coronary heart disease accompanied with anxiety and depression
SONG Xiuli,CUI Minghu,GENG Li. Clinical study of venlafaxine in the treatment of patients with coronary heart disease accompanied with anxiety and depression[J]. Journal of Binzhou Medical College, 2011, 0(4): 277-278,281
Authors:SONG Xiuli  CUI Minghu  GENG Li
Affiliation:SONG Xiuli1 CUI Minghu1 GENG Li2 1 Department of Psychiatry,Binzhou Medical University,Binzhou 256603,2 Department of Pathogen Biology
Abstract:Objective To observe the efficacy of venlafaxine in the treatment of patients with coronary heart disease and anxiety and depression.Methods 196 patients of coronary heart disease were enrolled in this study.52 cases were founded accompanied with depression and anxiety by the Zung Self-Rating Anxiety Scale(SAS)and the Zung Self-Rating Depression Scale(SDS).They were randomly divided into research group with venlafaxine capsules plus routine treatment and control group with routine treatment for 8 weeks.comp...
Keywords:venlafaxine  coronary heart disease  anxiety  depression  
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