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CD147、MMP-9与VEGF在肾细胞癌中的表达及其临床意义
引用本文:王苏春,王禾,秦卫军,孙航,顾汝军.CD147、MMP-9与VEGF在肾细胞癌中的表达及其临床意义[J].蚌埠医学院学报,2011,36(11):1194-1197,1200.
作者姓名:王苏春  王禾  秦卫军  孙航  顾汝军
作者单位:解放军第82医院149临床部,外科,江苏,连云港,222042;第四军医大学西京医院,泌尿外科,陕西,西安,710032
摘    要:目的:探讨白细胞分化抗原147(CD147)、基质金属蛋白酶-9(MMP-9)与血管内皮生长因子(VEGF)在肾细胞癌(RCC)组织中的表达及其与肾癌组织发生、肿瘤侵袭和转移的关系.方法:采用免疫组织化学SP法,检测107例RCC组织、10例正常肾组织中CD147、MMP-9与VEGF的表达情况,分析其表达与RCC的临...

关 键 词:肾肿瘤  白细胞分化抗原147  基质金属蛋白酶-9  血管内皮生长因子  肿瘤侵袭  肿瘤转移

The expressions and their significances of CD147,matrix metalloproteinase-9 and vascular endothelial growth factor in renal cell carcinoma
WANG Su-chun,WANG He,QIN Wei-jun,SUN Hang,GU Ru-jun.The expressions and their significances of CD147,matrix metalloproteinase-9 and vascular endothelial growth factor in renal cell carcinoma[J].Journal of Bengbu Medical College,2011,36(11):1194-1197,1200.
Authors:WANG Su-chun  WANG He  QIN Wei-jun  SUN Hang  GU Ru-jun
Institution:WANG Su-chun1,WANG He2,QIN Wei-jun2,SUN Hang2,GU Ru-jun1
Abstract:Objective:To study the expressions of CD147,Matrix metalloproteinase-9(MMP-9) and vascular endothelial growth factor(VEGF) in renal cell carcinoma(RCC),and explore their correlations with tumor growth,tumor invasion and metastasis.Methods:The expressions of CD147,MMP-9 and VEGF were detected by immunohistochemical SP method in tissue from the carcinoma(RCC,n=107) and normal renal tissue(n=10).The relationships between the expressions and clinical pathology were analyzed,and the correlations among CD147,MMP-...
Keywords:renal neoplasm  CD147  matrix metalloproteinase-9  vascular endothelial growth factor  invasion  metastasis  
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