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162例脊髓灰质炎灭活疫苗安全性调查
引用本文:刘美霞.162例脊髓灰质炎灭活疫苗安全性调查[J].中国现代医生,2011,0(26):15-16.
作者姓名:刘美霞
作者单位:山东省胶州市胶东街道办事处卫生院,山东胶州,266300
摘    要:目的了解注射型脊髓灰质炎灭活疫苗与口服脊髓灰质炎减毒活疫苗不良反应发生率的差异,为预防接种工作开展提供科学依据。方法选取胶州市3处具备接种脊髓灰质炎灭活疫苗许可的接种门诊2010年1月1日~12月1日接种脊髓灰质炎灭活疫苗的162名儿童作为观察对象,同时选取该3处门诊同期按种脊髓灰质炎减毒活疫苗的150名儿童作为对照,对比两者不良反应发生率的差异。结果两组儿童均无严重异常反应发生,一般不良反应发生率无差异(P〉0.05)。结论脊髓灰质炎减毒活疫苗现阶段仍是健康儿童预防脊髓灰质炎免疫的首选疫苗,对怀疑有免疫缺陷的儿童,建议选用脊髓灰质炎灭活疫苗替代脊髓灰质炎减毒活疫苗。

关 键 词:脊髓灰质炎灭活疫苗  脊髓灰质炎减毒活疫苗  不良反应

Safety Investigation of 162 Cases with Inactivated Poliovirus Vaccine
Authors:LIU Meixia
Institution:LIU Meixia Jiaodong Subdistrict Office Health Center,Jiaozhou 266300,China
Abstract:Objective To evaluate the safety of the inactivated poliovirus vaccine(IPV),compared with oral poliovirus vaccine(OPV).Methods One hundred sixty two children inoculated with IPV and one hundred fifty children inoculated with OPV during the period between January 1,2010 and December 1,2010 in Jiaozhou city of Shandong province were followed up and analyzed.Results No serious adverse reactions had been observed for both groups,and there was no difference in the occurrence rate of common unfavorable reactions ...
Keywords:Inactivated poliovirus vaccine  Oral poliovirus vaccine  Adverse reaction  
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