急性脑梗死C反应蛋白增高的临床意义分析

目的探讨急性脑梗死患者血清中C反应蛋白（CRP）水平变化与疾病严重程度的关系。方法采用胶乳增强透射比浊法测定65例脑梗死患者入院24h内血清CRP含量，并与对照组进行研究比较，同时将脑梗死患者按临床神经功能缺损程度评分标准进行评分，分为轻、中、重三组。结果急性脑梗死患者血清CRP浓度明显升高（P〈0．01）。血清CRP含量与神经功能缺损程度呈正相关（P〈0．01），重型组脑梗死患者血清CRP含量高于轻、中型组。结论CRP参与了脑梗死炎症反应的过程，CRP水平测定对脑梗死严重程度及预后评估有重要意义。

Acute Cerebral Infarction C-reaction Protein Analysis of the Clinical Significance

Objective To investigate the serum of patients with acute cerebral infarction in C -reactive protein （ CRP ） levels and the disease severity and prognosis of relationship, and the cerebral infarction prognosis evaluation. Methods Using latex enhanced transmission turbidimetry determinate the CRP content of 65 patients with cerebral infarction within 24 hours, and the level was compared with control group. The cerebral infarction patients were divided into three groups by clinical neurologic impairment score. Results The CRP level of patients with acute cerebral infarction was significantly elevated （ P 〈 0.01 ）. The content of CRP positively related with the neural function deficit （P 〈 0.01 ）. The CRP level of severe group was higher than that of light and medium group. Conclusion CRP is involved in cerebral infarction during inflammation, and CRP levels detection has important significance to assess the severity of cerebral infarction.