医院感染的病原菌分布及耐药性分析

目的分析医院感染的病原菌分布及耐药性,为临床合理用药和控制医院感染提供依据。方法对2007～2009年住院患者发生感染的病原菌及耐药情况进行回顾性分析。结果住院患者医院感染部位以呼吸道为主,占55.98%;病原菌以革兰阴性杆菌为主,占53.19%;细菌的耐药性普遍较高。结论医院感染病原菌以革兰阴性杆菌为主导,对常用的抗菌药物耐药性较高,常为多药耐药;加强病原菌分布及耐药性监测,对指导临床合理用药,减少多重耐药菌产生,降低医院感染率具有重要意义。

Analysis of distribution of pathogens in nosocomial infection patients and their antibiotic resistance

Objective To analyze the pathogens causing nosocomial infection and their antibiotic resistance,and provide the guidance for the clinical rational administration and decrease the nosocomial infection.Methods Retrospective analysis was performed on the drug resistant conditions of pathogenic bacteria in nosocomial infection in our hospital from 2007 to 2009.Results Respiratory infection was the main one,with the infection rate being 55.98%;The main pathogenic bacteria were the Gram-negative bacillus （53.19%）.The monitoring of the drug resistance showed the rate of the drug fast was rather high.Conclusion Gram-negative bacillus are the main pathogens leading to nosocomial infection and have higher tolerance against common antibiotic;Enhanced monitoring on pathogenic bacteria distribution and drug resistance analyses of nosocomial infection in patients can benefit the clinical rational administration of the depression of multidrug-resistant bacteria,and the decrease of nosocomial infection.