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Protein-losing gastropathy associated with autoimmune disease: successful treatment with prednisolone
Authors:Toshihiro Aoki  Noriyuki Noma  Ichiro Takajo  Jun-Ichi Yamaga  Masaaki Otsuka  Hiroaki Yuchi  Naoto Ishikawa  Haruhiko Inatsu  Jun-Ichiro Sakata  Yushiro Asada  Tanenao Eto
Affiliation:(1) First Department of Internal Medicine, Department of Pathology, Miyazaki Medical College, 5200 Kihara, Kiyotake, Miyazaki 889-1692, Japan, JP;(2) Department of Pathology, Miyazaki Medical College, Miyazaki, Japan, JP
Abstract:99m Tc-labeled human serum albumin scintigram showing abnormal radioactivity in the stomach. Endoscopic gastric biopsies revealed nonspecific inflammation, but marked intramural edema. Based on a slight elevation of antinuclear antibody level, autoimmune disease was suspected to be involved in this patient. Administration of prednisolone, as a diagnostic therapy, alleviated the hypoproteinemia, hypoalbuminemia, and hypercholesteremia. These findings suggest that an autoimmune mechanism could have been involved in this case of protein-losing gastropathy. Received: September 4, 2000 / Accepted: February 23, 2001
Keywords:: protein-losing gastropathy  prednisolone  systemic lupus erythematosus
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