电刺激小脑顶核对重型颅脑损伤血液流变学的影响

目的探讨重型颅脑损伤后血液流变学改变与电刺激小脑顶核(FN)疗效之间的关系。方法将60例重型颅脑损伤患者随机分为电刺激FN组(30例)和对照组(30例)。观察治疗前、后日常生活活动能力(ADL)评分及血液流变学指标的变化。结果治疗后电刺激FN组ADL评分为74.32±23.59分,对照组评分为60.12±19.5分,两组比较有显著性差异(P<0.05),电刺激FN组疗效明显优于对照组。电刺激FN组血液流变学指标与对照组比较有显著性差异(P<0.05)。结论重型脑外伤后可出现血液流变学异常,电刺激FN治疗可改善重型颅脑损伤血液流变学及临床疗效。

Effect of electrical stimulation of the fastigial nucleus on blood rheology in patients with severe traumatic brain injury

Objective:To investigate the effect of electrical stimulation of the fastigial nucleus on the blood rheology in patients with severe traumatic brain injury and explore the clinical significance.Methods:60 patients with severe traumatic brain injury were randomly divided into electrical stimulation to the fastigial nucleus group (30 cases) and control group (30 cases). All the patients were evaluated with activities of daily living(ADL),while blood rheology in these 60 patients was measured before and after a period(once a day for 20 days) of treatment. Results: After 20 days of treatment,ADL of the electrical stimulation group was 74.32±23.59, while ADL of control group was 60.12±19.5, there was significant difference between the two groups(P<0.05); The blood rheology of electrical stimulation group was significantly different from the control group (P<0.05).Conclusion:The electrical stimulation to the fastigial nucleus can improve the blood rheology of the patients with severe traumatic brain injury and elevate therapeutic effect; determination of blood rheology can be used for estimating the degree of traumatic brain injury.